{"product_id":"tr-pro-tissue-repair","title":"TR Pro+ - Tissue Repair","description":"\u003cp\u003eTissue Repair Pro is a hydrogel that helps damaged skin by creating an environment that supports the healing process. TR Pro+® hydrates skin internally whilst providing a barrier to reduce transepidermal water loss, is able to cool and soothe skin and is effective in reducing the irritation and redness that often follows aesthetic and other minor surgical procedures.\u003c\/p\u003e\n\u003cp\u003eKey Ingredients:\u003c\/p\u003e\n\u003cp\u003e- Beta-glucan (Glucoprime®) – a naturally derived sugar that is purified from the cell wall of baker’s yeast which has immunomodulatory properties that support skin regeneration\u003c\/p\u003e\n\u003cp\u003e- Triethanolamine – balances the pH of the gel to avoid irritation to your skin\u003c\/p\u003e\n\u003cp\u003e- Carbomer – allows the gel to retain water to provide you with a soothing texture and leave your skin looking bright\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cmeta charset=\"UTF-8\"\u003e\u003cspan\u003eWhen TR Pro+® is applied topically, the Glucoprime® moves between the cells of the epidermis to the dermis where it comes into contact with macrophages. These macrophages are the ‘guard cells’ and are on alert for foreign pathogens like bacteria and yeast.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eTR Pro+® stimulates macrophages to manage the healing process\u003c\/p\u003e\n\u003cp\u003eHealing is a complex process that involves many different cellular components being switched on and off at the appropriate time and in the correct concentrations. Macrophages are the cells that coordinate the healing process which occurs in four phases – haemostasis, inflammation, proliferation and remodelling.\u003c\/p\u003e\n\u003cp\u003eAs the healing process moves from inflammation to proliferation, the macrophages transition from the M1 to the M2 type and adjust the environment to one which supports skin regeneration. M2 macrophages produce a different array of cytokines and growth factors which enables the production of collagen, the restoration of the barrier function and the generation of new capilliaries. This proliferative phase may last for 4-24 days.\u003c\/p\u003e\n\u003cp\u003eM2 macrophages are essential to build new tissue through the generation of types I and III collagen. The tissue regeneration bought about by TR Pro+® is effective for medical procedures (eg: excision, biopsy, skin cancer removal) as well as aesthetic procedures (eg: laser, all types of skin needling and chemical peels).\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eTR Pro+® has been shown in laboratory studies to increase the number of M2 macrophages and in this way accelerate healing and improve skin quality (Mills et al. 2024).\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eHydrogels are the wound dressing of choice and \u003cmeta charset=\"UTF-8\"\u003e\u003c\/span\u003ecan benefit all stages of healing:\u003c\/p\u003e\n\u003cp\u003eCan be used for different types of wounds (closed, open, weeping or dry)\u003c\/p\u003e\n\u003cp\u003eCleansing phase: supports the removal of exudate, cell debris, foreign bodies and germs (autolytic debridement)\u003c\/p\u003e\n\u003cp\u003eGranulation phase: optimally moisturise and provide a hydrated matrix which promotes cell migration into the wound, and supports collagen synthesis and cross-linking\u003c\/p\u003e\n\u003cp\u003eReparative phase: re-epithelialisation is promoted by division of keratinocytes, optimally supplied with oxygen.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eTR Pro+® supports skin regeneration in many ways:\u003c\/p\u003e\n\u003cp\u003e- Film-forming, Flexible, Full Contact\u003c\/p\u003e\n\u003cp\u003eTR Pro+® dries to form a thin, transparent and durable protective film that stays in constant contact with the skin.\u003c\/p\u003e\n\u003cp\u003e- Wound Healing and Scar Formation\u003c\/p\u003e\n\u003cp\u003eTR Pro+® absorbs exudate leading to improved wound healing5. Increased hydration provides an environment favourable to normal scar formation (Muthuramalinga et al. 2019).\u003c\/p\u003e\n\u003cp\u003e- Protection\u003c\/p\u003e\n\u003cp\u003eTR Pro+® provides a barrier that protects against microbial infection while at the same time allowing the skin to breathe (Pillai et al. 2005).\u003c\/p\u003e\n\u003cp\u003e- Cooling Effect\u003c\/p\u003e\n\u003cp\u003eTR Pro+® provides a cooling effect to soothe damaged skin and helps relieve pain and itching. Heat generated from cosmetic procedures is able to dissipate freely (Pillai et al. 2005).\u003c\/p\u003e\n\u003cp\u003e- Stops Bleeding\u003c\/p\u003e\n\u003cp\u003eTR Pro+® acts as a haemostatic agent to stem bleeding and manage exudate (Madaghiele et al. 2014).\u003c\/p\u003e\n\u003cp\u003e- Easy to Use and Non-reactive \u003c\/p\u003e\n\u003cp\u003eTR Pro+® can be applied once daily, is non-greasy, and can easily be removed from clothes. TR Pro+® is neutral pH, and does not contain any preservatives, fragrances, or parabens making it suitable for people with sensitive skin.\u003c\/p\u003e","brand":"Loren Ashley Skin Clinic","offers":[{"title":"Default Title","offer_id":54314523590969,"sku":null,"price":52.0,"currency_code":"NZD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0683\/7606\/8409\/files\/IMG_2786.webp?v=1786150372","url":"https:\/\/shop.lorenashleyskin.co.nz\/products\/tr-pro-tissue-repair","provider":"Loren Ashley Skin Clinic","version":"1.0","type":"link"}